FORMULATION AND EVALUATION OF HERBAL BUCCAL FILM OF TULSI (Ocimum sanctum) FOR THE MANAGEMENT OF MOUTH ULCERS: A Review
Neeraj Bharti1, Arjun Singh2, Yusra Ahmad3
1Research Scholar, 2Assistant Professor, 3H.O.D.,
Faculty of Pharmacy, Veer Madho Singh Bhandari Uttrakhand Technical University,
Dehradun, Uttrakhand, India
Abstract: Oral health is a vital component of general health, and mouth ulcers can substantially impact an individual’s daily life. They sting, get all swollen, and suddenly even basic stuff like eating or talking becomes a hassle. These little sores don’t just bug you for a bit they really drag down your mood and your routine. And they show up for all kinds of reasons. Maybe you bit your cheek, caught some infection, missed out on certain vitamins, got stressed, or your immune system’s just acting up. Most of the usual fixes creams, gels, pills only give quick relief. They can be a pain to use, bring some annoying side effects, and let’s face it, most people don’t bother sticking with them for long. Lately, though, herbal remedies are getting a lot more attention. People see them as safer, they tend to help with more than one thing, and overall, folks just seem to tolerate them better. Tulsi (Ocimum sanctum) really stands out. It helps with inflammation, fights germs, acts as an antioxidant, soothes pain, and speeds up healing. That makes it a pretty strong contender for treating mouth ulcers. Now, there’s something new mucoadhesive buccal films. These are thin, bendy strips you stick right on the sore. They slowly release Tulsi exactly where you need it. They’re simple to use and don’t taste bad, either. This study’s all about making and testing those Tulsi buccal films. We used a solvent casting method, mixing different polymers and plasticizers to get the films just right strong, flexible, and sticky enough to stay put. We checked everything: strength, stickiness, how much Tulsi gets delivered, how quickly it’s released, how much water the films soak up, and how well they hold up over time. The results? Pretty solid. The films are tough, deliver Tulsi steadily, stick well, and last. Tulsi buccal films really look promising. They ease pain, bring down swelling, help you heal faster, and fight off infections all while making it easier for people to actually follow through with treatment. This research proves that mixing traditional herbal medicine with new ways of delivering it can give us a safer, more effective way to treat mouth ulcers.
Keywords: Buccal films; Ocimum sanctum; Mouth ulcers; Herbal drug delivery system; Mucoadhesive polymers; Oral mucosa
VOLUME 10 ISSUE 03 2026: 14 – 29