ABSTRACT:
Background: Aortic stenosis is pathological condition in which aortic valve which is present between left ventricle and aorta becomes narrowed. Patients with aortic stenosis had high mortality rate due to left ventricular dysfunction which leads to improper blood supply to the body and associated coronary artery disease. Echocardiography is the modality to evaluate cardiac disease. Patients refer on further modalities for confirmation of disease or preoperative evaluation. Objective: To investigate feasibility of computed tomography coronary angiography in diagnosing left ventricle dysfunction in patients with aortic stenosis. Methodology: This cross-sectional descriptive study conducted at Punjab Institute of Cardiology, Lahore. Sample size of our research was 40. Results: The participants ranged in age from 17 to 73 years (72.5%male), with the majority of the patients were of the age between 21 to 40 years. 12.5% of those aged over 65 while 87.5% were between 17 to 64 years affected with aortic stenosis. 9(22.5%) patients had congenital bicuspid aortic valve causing aortic stenosis while 31(77.5%) had trileaflet aortic valve which acquire aortic stenosis. 13(32.5%) patients out of 40 had LVEF < 50% out of which 6(46.2%) patients had dilated LV with moderate LV systolic dysfunction and 7(53.8) patients had dilated LV with severe LV systolic dysfunction were diagnosed on CTCA. Conclusion: CTCA is more feasible for early and accurate diagnosis of left ventricular dysfunction in aortic stenosis patients. CTCA can improve the diagnostic potential and treatment plans for patients with aortic stenosis and associated left ventricular dysfunction.
Key words: Computed tomography coronary angiography (CTCA), Left ventricle (LV), Aortic Stenosis (AS), Ejection Fraction (EF)