Faculty of Pharmacy, Veer Madho Singh Bhandari Uttarakhand Technical University,
Dehradun, India

Abstract: Hemovigilance includes an organized overview of monitoring and managing any negative outcomes of blood transfusion along with safeguarding the donors and recipients of blood transfusions. This study articulates systematically the theory, types and ways of putting the hemovigilance systems into practice in micro and macro health institutions. It discusses the role of structured, streamlined, and controlled transfusion safety reporting along with databases and feedback systems. It encompasses the systems of primary donor and recipient hemovigilance, operational and laboratory monitoring, near and other systems for other countries. It analyses current constraints to reporting, definitional inconsistencies, and digital resource deficits, while proposing system effectiveness improvements. It emphasizes system strengthening improvements to artificial intelligence, automatic electronic reporting, donor-recipient system feedback, and definitional globalization, particularly in resource constrained environments. It emphasizes the necessity of improved structured systems to promote transfusion medicine safety and efficient practice globally.

Keywords: Hemovigilance, Blood Transfusion Safety, Donor Monitoring, Recipient Reactions, Transfusion Medicine, Surveillance Systems, Artificial Intelligence, Near-Miss Events.

VOLUME 10 ISSUE 03 2026: 68 – 84